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Cleveland Clinic: First Patient to Receive Breast Cancer Vaccine Shares Health Journey

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The vaccine targets a lactation protein called α-lactalbumin, which is no longer found after lactation in normal, aging tissues but is present in most triple-negative breast cancers. If breast cancer develops, the vaccine is designed to prompt the immune system to attack the tumor and keep it from growing. (Courtesy: Cleveland Clinic)

#USA, April 17, 2023 – During a typical day at work, Jennifer Davis received an unexpected call that changed her life. A nurse on the other end of the line delivered the news Jennifer had triple-negative breast cancer. The mother of three recalls feeling terrified. She didn’t know how she was going to tell her family. After receiving the diagnosis, Jennifer knew she wanted to take advantage of every treatment option available. Through her driven search for answers, she became the first person to participate in a novel study at Cleveland Clinic for a vaccine that aims to eventually prevent triple-negative breast cancer.

“When I found out I was the first person to receive the vaccine, I was excited. I was thrilled. The trial has given me a lot of hope,” says Jennifer, a registered nurse from Lisbon, Ohio.  

Jennifer’s health journey started in February 2018 when she felt a lump in her breast. She went to a local hospital for follow-up, and her first biopsy showed no evidence of cancer. Months went by, and Jennifer says the lump grew. She listened to her body and continued to get it checked. Jennifer eventually received another biopsy after doctors detected abnormalities during an ultrasound. Her diagnosis was confirmed about one week later, and she sought a second opinion for her treatment.  

“I knew I wanted to go to Cleveland Clinic, so I had my first appointment there shortly after. I met my entire care team within my first few appointments and had a complete treatment plan. I was very happy with my team and was anxious to get started,” says Jennifer.  

As part of the plan, she underwent multiple rounds of chemotherapy and radiation. She also had a double mastectomy performed by breast surgeon Zahraa AlHilli, MD.  

“After the double mastectomy, I was adamant while in recovery about wanting to know what they found and whether the cancer had spread. Dr. AlHilli was able to get clear margins, and there were no signs the cancer had spread anywhere else,” says Jennifer.  

After undergoing treatment, it was during her follow-up appointments with breast medical oncologist Megan Kruse, MD, she learned about the breast cancer vaccine clinical trial.  

The vaccine is based on pre-clinical research led by the late Vincent Tuohy, PhD, who was the Mort and Iris November Distinguished Chair in Innovative Breast Cancer Research at Cleveland Clinic’s Lerner Research Institute. The vaccine targets a lactation protein called α-lactalbumin, which is no longer found after lactation in normal, aging tissues but is present in most triple-negative breast cancers. If breast cancer develops, the vaccine is designed to prompt the immune system to attack the tumor and keep it from growing.  

Research nurse coordinator Donna Lach administers the third dose of the breast cancer vaccine to Jennifer. (Courtesy: Cleveland Clinic)

“Triple-negative breast cancer is the form of the disease for which we have the least effective treatments,” said G. Thomas Budd, MD, breast medical oncologist and principal investigator for the breast cancer vaccine trial. “Long term, we are hoping this can be a true preventive vaccine that would be administered to cancer-free individuals to prevent them from developing this highly aggressive disease.”  

Jennifer is involved in phase 1a of the study, which includes patients who completed treatment for early-stage, triple-negative breast cancer within the past three years and are currently tumor-free but at high risk for recurrence.  

“There is no medication I take to make sure there’s not a recurrence,” says Jennifer. “With every ache and pain, your mind goes to the worst-case scenario. So, I was very excited when I heard about the vaccine.”  

In October 2021, Jennifer became the first patient to enroll in the trial and receive the first dose of the vaccine. “I didn’t think twice about getting the vaccine and haven’t looked back since.”  

Dr. Kruse says, “For a long time with triple-negative breast cancer, the overarching theme patients talked about is how they’re going through all this treatment but still feeling like they’re destined to have the cancer return. I think having the hope of this vaccine study where we can potentially turn that around and have some optimism as we approach the future for these patients is the best part.”  

Over the course of the study, Jennifer and other participants received three doses of the vaccine. The vaccinations were each given two weeks apart, and the participants were closely monitored for side effects and immune response. She received her last dose in November 2021 and has not noted any major side effects.  

“My husband went with me for the first vaccine. Then my mom went with me for the second and third,” says Jennifer. “I don’t know if I ever went to an appointment at Cleveland Clinic by myself, and that support has meant a lot to me.”  

Jennifer is hopeful about the vaccine trial and encourages others to stay positive amid the ongoing research. (Courtesy: Cleveland Clinic)

In February 2023, Cleveland Clinic researchers launched the next step in their study of the vaccine. The phase 1b clinical trial, conducted in partnership with Anixa Biosciences, Inc., focuses on individuals who are cancer-free, at high risk for developing breast cancer and have decided to voluntarily undergo a prophylactic mastectomy to lower their risk.  

Meanwhile, Jennifer, now 46 years old, continues to follow up with Dr. Kruse as she nears her fifth year of being in remission. Although it will take years to fully understand the vaccine’s effectiveness, she’s eager for what’s to come and hopes her story can help others diagnosed with breast cancer.  

“Even though you’re going to have days where you’re not positive, where you feel terrible – keep moving forward. If the vaccine works the way they want, it could prevent triple-negative breast cancer one day,” says Jennifer.  

Editor’s note: Dr. Tuohy was inventor of the technology, which Cleveland Clinic exclusively licensed to Anixa Biosciences. He was entitled to a portion of the commercialization revenues received by Cleveland Clinic and also held equity in the company.

Related Institutes: Lerner Research InstituteCleveland Clinic Cancer Center

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UN Reports Ebola Outbreak Expands in DRC; Bahamas Monitors Two Recent Arrivals

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The Bahamas, May 29, 2026 – The Ebola outbreak in the Democratic Republic of the Congo (DRC) continues to expand, with United Nations officials now warning that the disease has spread across multiple eastern provinces and become the third-largest Ebola outbreak on record.

According to the UN Office for the Coordination of Humanitarian Affairs (OCHA), as of May 26 the outbreak had reached 13 health zones in Ituri, North Kivu and South Kivu provinces. More than 1,000 suspected cases have been reported, including 121 confirmed infections and 17 deaths. Six healthcare workers are among those who have died.

The United Nations says humanitarian teams remain actively engaged in treatment, surveillance, community outreach and disease containment efforts. However, the response is being complicated by insecurity, population movement and restrictions affecting the delivery of supplies and personnel.

While the outbreak remains confined to Africa, authorities in The Bahamas recently activated emergency health protocols after two men who had spent time in the Democratic Republic of the Congo arrived at Lynden Pindling International Airport aboard a British Airways flight.

The Ministry of Health confirmed the travelers were isolated after presenting low-grade fevers upon arrival on May 22. Officials later reported that the fevers subsided and neither individual displayed symptoms consistent with Ebola Virus Disease.

The two men, identified as a British national residing in Australia and a French national, were transferred to the Modular Unit at Princess Margaret Hospital for continued monitoring.

Health officials emphasized that there are currently no confirmed Ebola cases in The Bahamas and assessed the risk to the public as low.

Still, the growing outbreak overseas has prompted increased vigilance. Health Minister Dr. Michael Darville said the government is reviewing whether additional travel measures may be necessary for countries affected by the outbreak.

The United Nations this week announced up to US$60 million in emergency funding to support the Ebola response in the Democratic Republic of the Congo and neighboring countries, warning that rapid action remains critical to preventing further spread.

Angle by Deandrea Hamilton. Built with ChatGPT (AI). Magnetic Media — CAPTURING LIFE.

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Turks & Caicos Islands Hospital Celebrates International Emergency Medicine Day 2026

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May 27, 2026 – Today, Turks & Caicos Islands Hospital, InterHealth Canada proudly joins the global healthcare community in observing International Emergency Medicine Day, recognizing and celebrating the extraordinary dedication, courage, and compassion of emergency healthcare professionals who stand on the frontlines of patient care every single day.

International Emergency Medicine Day is observed annually on May 27 to promote professional, competent, and timely emergency medical care for all people around the world. Emergency medicine professionals provide lifesaving care for patients facing critical illnesses and injuries, often during the most difficult and uncertain moments of their lives.

At the heart of every emergency department is a team of highly skilled and committed professionals, physicians, nurses, support staff, and allied healthcare professionals who work tirelessly together to save lives and provide hope when it is needed most.
Emergency medicine focuses on the rapid assessment and treatment of life-threatening conditions such as heart attacks, strokes, cardiac arrest, trauma, respiratory failure, severe bleeding, and sepsis. Emergency teams care for patients of all ages and backgrounds, ensuring that patients receive timely and effective care according to the urgency of their condition through the triage system.

As the safety net of the hospital, the Emergency Department operates 24 hours a day, seven days a week, serving patients during natural disasters, humanitarian crises, and daily medical emergencies. The demanding nature of emergency care requires teamwork, resilience, professionalism, and compassion.

“Today we recognize and celebrate the incredible individuals who dedicate themselves to emergency medicine,” said Dr Monnique-Chadee Waite, Head of the Emergency Department. “Our emergency team is there during some of the toughest moments in people’s lives. Their commitment, expertise, and compassion make a difference every single day. Teamwork truly makes the dream work, and we deeply appreciate every member of our department.”

Shantell Gardiner, Nurse Manager of the Emergency Department, highlighted the dedication of the nursing team and support staff. “Emergency nursing requires strength, compassion, quick thinking, and teamwork. Every day our nurses and support teams provide comfort and care to patients and families during stressful and emotional situations. I am incredibly proud of the dedication and professionalism our team demonstrates every single shift. We appreciate each and every member of our Emergency Department family for the vital role they play in saving lives.”

Dr Dawn Perry-Ewing, Chief of Medical Services, added, “Emergency medicine professionals are among the most vital frontline caregivers in healthcare. Their ability to respond quickly, work collaboratively, and remain calm under pressure saves countless lives. We thank them for their unwavering dedication and for continuously striving to provide safe, competent, and compassionate care to every patient.”

Dr Denise Braithwaite-Tennant, Chief Executive Officer, also expressed gratitude to the department. “On this International Emergency Medicine Day, we extend our sincere appreciation to our emergency teams for their extraordinary service and sacrifice. They represent the very best of healthcare, courage, teamwork, professionalism, and humanity. We thank them for standing ready every day and night to care for our community when it matters most.”

The Turks & Caicos Islands Hospital also acknowledges the importance of maintaining a safe and respectful environment within Emergency Departments. Emergency Departments follow a system called Triage, where patients are treated according to the severity and urgency of their condition rather than arrival time. Supporting emergency healthcare workers and respecting the triage process helps medical teams provide safer, faster, and more compassionate care to all patients.
Today and every day, the Turks & Caicos Islands Hospital, InterHealth Canada salutes its Emergency Department team for their dedication, resilience, and lifesaving work.

Teamwork makes the dream work and we appreciate you.

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Grand Turk Residents Fear Norovirus-Linked Cruise as Health Ministry Approves Docking

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Turks and Caicos, May 22, 2026 – Residents in Grand Turk raised concerns last week after a cruise ship previously linked to a major norovirus outbreak was cleared to dock in the Turks and Caicos Islands days after passengers were reportedly denied disembarkation in The Bahamas over health fears.

According to the US Centers for Disease Control and Prevention, the outbreak sickened 115 people — including 102 passengers and 13 crew members — during a voyage which ran from April 28 to May 11. The illnesses involved symptoms commonly associated with norovirus, including vomiting and diarrhea.

The outbreak became public on May 7 and quickly triggered concern across the region.

Authorities in Nassau reportedly refused to allow passengers off the vessel because of public health concerns connected to the outbreak.

That decision later fueled anxiety among some Turks and Caicos residents when the ship proceeded to Grand Turk on May 15.

Residents’ concerns were not without cause.

Norovirus is a highly contagious viral illness often associated with cruise ships, hotels, schools and other environments where large groups of people share close quarters. The virus primarily causes sudden vomiting, diarrhea, stomach cramps and nausea, and spreads rapidly through contaminated food, water, surfaces and person-to-person contact.

According to the US Centers for Disease Control and Prevention, most healthy people recover within one to three days, but norovirus can become serious — and occasionally fatal — for elderly individuals, young children and people with weakened immune systems because of severe dehydration. While the overall fatality rate is considered very low, the CDC estimates norovirus contributes to hundreds of deaths annually in the United States, mainly among vulnerable populations.

The Turks and Caicos Ministry of Health and Human Services had said in a press statement on May 15, it believed the risks had been effectively neutralized before the vessel arrived in Grand Turk.

In a statement issued Thursday, the Ministry said the ship had already returned to Florida, where passengers disembarked and “comprehensive sanitization and deep-cleaning procedures were completed” before operations resumed.

The Ministry also stressed that its Public Health Team maintained “close and continuous communication” with the ship’s medical personnel, Carnival Cruise Line officials and stakeholders at the Grand Turk Cruise Centre before approving the docking.

Routine inspections and standard port health procedures were also carried out, according to officials.

The Ministry further reassured the public that there were “currently no public health concerns” associated with the vessel’s arrival.

Still, the situation once again highlighted the delicate balancing act Caribbean nations face between protecting public health and sustaining tourism economies heavily dependent on cruise arrivals.

Officials are now encouraging vendors, taxi operators, tour companies and businesses to continue practicing strong sanitation and hygiene measures as an added precaution.

Residents were also reminded that frequent handwashing remains one of the most effective ways to prevent the spread of norovirus and other infectious illnesses.

Angle by Deandrea Hamilton. Built with ChatGPT (AI). Magnetic Media — CAPTURING LIFE.

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